tf is compatible, however it makes geting starting items much more difficult.
Unobtainable items in TFC:
Wooden Planks (maybe, IDK if TFC's Plank blocks are compatible with the ore dictionary)
Cobblestone
Iron
Copper (well, not really, but it's not compatible with the ore dictionary)
Tin (same)
Glass (at least I think there's no way to "smelt" Sand/)
Emerald
Diamond (I don't think TFC Diamonds are equivalent to Vanilla Diamonds for crafting)
Anything related to the Nether or End
(Redstone's obtainable, though I don't remember how.)
IC2 Rubber, likely
Now try getting a Macerator.