Everything about the ultra-endgame of ChromatiCraft, especially Skystrike and the vacuum gun.
And, for your dose of something unrelated to Minecraft: Kraken black spiced rum. Superbly potent and remarkably drinkable.
I discovered back a bit ago that shots of Jim Beam Devil's Cut with Angry Orchard chasers does something magical to your mouth. Kraken is pretty tasty too, though.
Minecraft related, I just realized that ImmEng Powered Lanterns act as a Magnum Torch in regards to mob spawning. 32 block radius free of mobs for only 2RF/t, and they look awesome? Yes please.