You could, as you just said, build it in a far off place in your main world. As this could be the vanilla overworld there is no reliance on other mods for safety.
You could but without any form of chunk loading to keep a long line of shafts to your base, the base itself, and the reactor running, how do you keep it all running.
I always built my reactor in my base, only one i had a problem with it...
And hum chromaticraft solve this issue mostly which is another mod, sure, but by the same author and to help you out with Roc and Rec
I have no issue Using any and all of Reika's mods. I actually have built myself a 1.7.1 pack based around Reika's mods because i like them so much. I've added quite a few goodies like EU, iron chest, jabba, and utility mods like maps and inventory tweaks...You know all the little ones that just make playing more fun. The only major mod I added is Ender IO because I wanted something with conduits and cables and I really like that mod. But I am limiting myself to use RoC and ReC for power and processing.
So what are you using from Chromaticraft to help you? I have heard people mention the world rift as a way to transfer power kinda like a tesseract can. Is that what you are referring to? My world is only a few days old, so I am a long ways away from getting to that stuff, but having a plan to start with now would be good. Still haven't messed with Chromaticraft much other than gathering crystals while mining and laughing as I generate chunks and the towers obliterate mobs.