That rather depends on what you want to do. But simplest and most common is to use a ME interface. Items pumped by conduits into the interface enters the ME network. Items set to be kept in stock in the ME interface can be pumped out by the conduits.
I want that my items from my MFR machines (for example the grinders) get pumped trough ender IO item conduits into the ME storage, but I also want to be able to send items like wheat for my breeder from the ME storage trough the item conduits to the breeder.