Well, Redpower is not the ultimate mod that solves every problems, even if some people want to believe it.
But even then, when I see some people blaming all the lag on one mod, it hurts a bit.
If you want to talk about potential lag, IC2 machines can become a big source, if they have many over-clockers but no storage upgrades, for example.
And the ComputerCraft sorting, while it seems all great, it has a particular problem of being a little hard to put in place with a big flow of items.
That means that it will have trouble with dealing with the faster mining operations.
Well, that being said, these mining operations are also a source of lag, doing a lot of block update, constantly (RP quarry, max speed BC quarry, array of mining turtles with specialized mining programs...).
And if you don't sort the cobble, sand, sandstone, snow, basalt and marble, it significantly reduces the input anyway, so I guess that's fine.
In my opinion, the worse part of RP where lag is concerned are the micro blocks, because they demand additional calculations to be rendered, so when there are a lot of them, the FPS will go down significantly.
That's sad, because they are such an awesome building material...