Let's be honest here, how many people actually do bees the fully random way? I rush for industrious+imperial then do the majority of my breeding via alveary. There's still a little luck involved even with a mutator, but it's unlikely to take more than two breeding cycles unless you're doing something wrong (i.e. don't have the right foundation block). Even if you don't use a mutator, most of us use mutation-encouraging frames right from the start. If you actually did Extra/Magic Bees without using some form of RNG helper you'd be a little crazy, but basic forestry doesn't have a mutator and its frames only affect production chance, so let's not pretend we're doing bees "as originally intended." Add in being able to fine tune your bees' attributes with serums and we're already pretty OP compared to Sengir's original idea.
I personally dislike Gendustry, but the only change it makes that I'd actually call OP (compared to Extra Bees) is the ability to ignore the ill effects of boosting production chances too far (Gendustry allows you to ignore the ignoble trait). Even that is just packing more production into one block rather than spreading it out across several setups. Many people probably find that just fine.
On topic: I've heard good things about
this turtle script for bee breeding. It's an updated version of an older script that was always fairly popular on the CC forums, so I'd expect it to work pretty well.