Understood how they are Supposed to work. But, something is borking up the recipes in NEI. All you have to do is try it yourself.
What is very strange tho? You can make a single blood rune using the way I described (using the endoflame) but if you stick a stack of them in there, a blank product appears on right. If you remove things, not even if you leave just 1 of each, the end product stays blank. You have to literally just create a single blood rune, on at a time using a endoflame to get that blood rune. I haven't played since I posted so I haven't gone down the legit route, which I'm sure works. Just letting you know that something is borked.
Also, didn't see it mentioned. Poppy in altar gets sparkly then stops but no visual change in altar that anything but a poppy is in there, but a endoflame is in there now and when you pick it up it's an endoflame. Side note, my count doesn't go up inside inventory till I do a sort so something is definately bork borking.