Honestly any amount of sacrifice runes will help and to speed up the transfer with the tanks you need dislocation. Once you get to t5 it is honestly best to set up 3 seperate altars. One altar for sacrifice, one for crafting and the third for orb filling. The altars are set up very differently and if you need help with it just ask and i will be happy to give you my setups for them.Thanks for the response. I was already pumping blood in (the refractory hopper), at 20 LP per it isn't enough to make a significant difference. I hadn't realized that self sacrifice runes were craftable at tier 2, not sure if 4 of these would have been enough to help (with a tier 2 altar only 4 of the 8 runes are active).
It's academic now, I did it with 2 Notch apples. Mostly I'm curious if there was a better way.