1. Certus Quartz grinder, manual doubling (first few days)
2. TE3, automatic doubling but slow (first week)
3. IC2, fast doubling (second week and beyond)
4. Bees (mid game)
By the time I reach #4, I have no further need for increasing my production, my bees make everything for me at that point.
This is pretty much the way I look at it too. In my Monster LP I'm at:
1. Certus Quartz grinder. Easiest ore doubling to start.
2. EnderIO/TE3. EnderIO has some good small chance byproducts in the SAG Mill and can be "overclocked" with it's capacitors.
3. Magic Crpos (decent alternative to bees, most of the same types of products and about the same level of "grindy-ness")
4. QuarryPlus + Mystcraft worlds. At this point, brute force is easier than efficiency so the same simple setup from #2 can easily be piped/wired/powered and expanded to keep up.
I dread IC2Ex and the stupid plate smashing and in general it has the feel of Gregtech that leaves a dirty taste in your mouth.
Mariculture is too dang hard to find solid info on. When I google recipes and plans, I get conflicting and outdated info for stuff like some freezer that's not even in Monster 1.1.2. Pair that with the odd ratios on everything, like limestone making 9/10ths of a bucket of quicklime and the crucible telling me it has 144Mb of something but that's enough for 1 ingot and it's not worth the bother.
Rotarycraft: The 5x processing needs so many resources and infrastructure and power that it goes in my book under neat tricks and Rube Goldberg contraptions. The sound and lag from RC is also a put off.
Factorization/Engineer's Toolbox: haven't tried either.