My tips:
Use only the RAM you need. Too much allotted RAM hurts fps. Tweaking RAM usage gave me twenty extra fps on integrated graphics. And this stopped stuttering for me.
You have too little RAM when you suffer extreme fps drops (0 fps for five seconds)
Turn off shaders and particles in the thermal expansion config. The tesseract shader kills fps on integrated graphics systems. And, overall, thermal expansion machines are not cpu friendly, but that may be bias. I have preferred to use rotarycraft for heavy processing.
I would also try the other tips.