Alright, kinda a copy cat. But here goes.
I was playing a server on Unleashed a while back. I set up a nuclear reactor to go with my supergen for IC2. I go up to go work on making some more components. The hole fit a cactus farm pretty well...
I have an IC2 nuke plant one too...
Back in the days when making an Ice CASUC nuke reactor was all the rage, I decided I was going to be a bit contrary just for the sake of it and devised a way to get even higher fuel efficiency -- firing the reactor in a very short burst with a very long cooldown (using a redpower timer and inverter) since it was full of nothing but fuel. This worked, but didn't give you stable enough power to be useful. So the idea struck me to build a lot of them and a redstone circuit to fire them in sequence (basically a series of repeaters, not that complicated, used a switch to test the circuit thoroughly before I did the next part). I set up all the reactors on the circuit, filled them all with fuel, rigged up the wiring and transformers to get the power going where it needed to, and placed the final bit of redstone (connecting the timer to the inverter) in the circuit to start the whole mess up. I even included a safety factor in my timing, running for only 2/3 of the maximum runtime before it would blow and giving it an extra 30s of cooldown (and I had a single reactor run like that for a long time with no issues).
The circuit started, it went through the first several reactors without a hitch. There was however a tiny wiring error that didn't come up until the appropriate reactor turned on, caused a tiny explosion which knocked out a single piece of redstone, which switched all the remaining reactors on with no way to turn them off in the ~3s it would take for them to blow.
In the end, a tiny IC2 wiring mistake caused a really, really impressive crater. Also, pulse-fired nuclear reactors would work, but oh dear god if you made even the tiniest mistake. Looking back at the idea, given the number of nuke reactors I was willing to build and fill I probably should have given each nuke plant it's own inverter so it would default to keeping the plant off -- then it would have been less likely to go up in that astounding chain of destruction.