as a side note, while testing stability for a server, we found that the multi-tiered dungeons, the amount of enemies spawned can destroy fps pretty quickly.
Ok, thats good to note. Its probably the lycanites, they seem to do that even without all the dungeon spawners.
Feel free to change the roguelike.cfg and reduce the levelMaxRooms, levelRange, and spawnFrequency to make them generate smaller and less often. If that dosnt help you can just remove the mod as it wont break anything or make any quests incompletable.