Yep, the ME Interface is a very powerful block, and where you can use it, it's way faster than any of the buses. I'm using it to import items into the system wherever feasible.
I'm wondering though: you who attach ME interfaces to tesseracts, how do you deal with possible overflow problems? I have two subnetworks with only formatted storage, but parts of your network must remain open in order to be able to take new items in, for instance when new stuff comes in or when you clear out your inventory. How you do prevent overflow from spilling into your main system, when everything goes into the network without a trashcan fork put in-between?