like blocks that do damage to entities that come in contact with them, like cactus? if so the extra utilities spikes (iron, gold, diamond), TC punjii sticks, TC ore berry bushes, there is a bush block from Twilight forest mazes that does damage, and Thaumcraft tainted soil either mutates them or damages them, don't remember which. There are various liquids that do damage too, sludge, sewage, lava, and liquid cryothem.
Also, I would like to see this cow dart system in action very, very much
Edit: Thaumic infusion may also allow you to make a block "act" as cactus, although I am not 100% sure on that