Ender IO is a cheap and easy way to process ores. Very easy to get a setup on day one. You can use the alloy smelter to make TE metals like electrum and invar to get an easier start in Thermal expansion. It also has some of the best cabling options. It's conduits can all go in one block. You can carry items, fluid, RF, redstone signal, now ME cable(latest version of Monster) in a single block that can be covered to hide everything. You can also use engineer's toolbox. It is probably the most complicated of the bunch. It is a multi machine process that can triple ores plus bonuses. You have to build a multi block kiln to make quicklime dust for the final processing. You start with a basic grinder and furnace and add on to it as your progress. Rotarycraft is capable 5x on common ores and up to 9x on rare ores. It requires a fair bit of infrastructure to get that much though.
To those talking about power issues.
Monster has a mod with one of the best power solutions i have seen. Use Engineer's Toolbox. Simply make a battery block with 1 or 2 inputs, and advanced storage upgrade, and 1 or 2ouputs. You can run RF or EU in or out of it. It converts everything internally. Use whatever generators you want and multiple mods machines on one power storage block. You also can use power converters.