I really like using me chests instead of drives because I can quickly find something that I recognize visually but can't recall the name of. That and with the prioritization numbering per chest, I can have my full inventory grouped to whatever listing fashion I want. No way I'll be able to do that in AE 2 though.... too many devices.
With some clever usage of dense cable and/or P2P tunnels, you can make use of every single one of the 32 channels that each face of the AE2 controller can provide, which means that you can connect 32 chests to that one face. By the time you actually manage to put things in all of those chests, you'll no doubt have some disks with things whose names you can remember (i.e. cobblestone, ores, ingots, wood, etc), and won't need to look through them, so you can put them in drives.
AE2 channels really aren't as big a deal as some people think. Tricky to manage and occasionally annoying, yes. But there are always several clever ways to solve almost any cabling problem, including using dense cables; P2P tunnels connected to your main network, a sub-network with its own controller, or their own ad-hoc network; or breaking your main network up unto several smaller sub-networks, as Algorithm demonstrates
here.