The short answer no.. UnLess minecraft itself requires it.. Which it does not.
I uprgraded from 1.4.7 to 1.5.2.. Which did require some Mods to be resett.
Resetting a mod is as easy as Loading you map in the new version without the mod, and having Forge or minecraft (not sure which one does it) delete everything from that mod in your world.
Then your turn off minecraft.. load the mod back up... Either start over... Or NEI the stuff you lost back in.
Takes some work but is possible.
The biggest killer is the new liquids in forge, and version 1.5.2. you will lose pretty much all of it.