An update to the existing information:
Extra Bees 1.5 and Forestry 2 have made changes to the Alveary such that it is now possible to get any bee to operate in any biome, but the more extreme the difference between the local climate and the climate you need, the more effort and resources you need to invest into the system. Expect to suddenly need to use MJ to keep the artificial climate stable as well.
It is considerably more cost-effective in the long-term to breed bees with universal heat and humidity tolerances, but also much harder.
Finally, a point that was never mentioned up until now: certain mutations require that the Queen is bred and working in a specific biome. You will need access to every vanilla biome to guarantee an efficient, low-cost breeding program.
Extra Bees 1.5 and Forestry 2 have made changes to the Alveary such that it is now possible to get any bee to operate in any biome, but the more extreme the difference between the local climate and the climate you need, the more effort and resources you need to invest into the system. Expect to suddenly need to use MJ to keep the artificial climate stable as well.
It is considerably more cost-effective in the long-term to breed bees with universal heat and humidity tolerances, but also much harder.
Finally, a point that was never mentioned up until now: certain mutations require that the Queen is bred and working in a specific biome. You will need access to every vanilla biome to guarantee an efficient, low-cost breeding program.
Easily the best location for a bee base is on the border between a Plains and Forest biome. It's not perfect but it provides the widest support for bee mutation in one place.